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Evaluating Dementia: Assessment for Treatable Causes

"Dementia" means an acquired, persisting skull is limited, they cause trouble by
decrease in mental functioning. Dementia crowding the brain. Subdural hematomas
is not a disease or a final diagnosis; and epidural hematomas are two other
instead, it refers to a category of space-occupying abnormalities that crowd
symptoms that can be the result of a the brain. These are masses of clotted
diverse group of conditions and blood usually caused by traumatic blows
diseases.Everyone with eyes and a brain to the head. The injuries producing the
of their own knows that dementia is a bleeding are not always remembered or, if
very common and serious problem, robbing remembered, might have been dismissed as
some people of their memories, ability to trivial at the time they occurred. These,
function independently and even their too, can be totally removed by a
personalities. As a community-based neurosurgeon.Normal pressure
neurologist, I see all too many cases of hydrocephalus is another cause of
dementia, but the part that worries me dementia responding to neurosurgery, but
the most is when patients, family members in this condition the surgeon doesn't
and even medical personnel assume that remove a mass-lesion. Instead, the
nothing can be done and don't even bother surgeon places a tube inside one of the
to evaluate for underlying brain's swollen fluid-chambers known as
causes.Although it is certainly true that ventricles, allowing the excessive
modern medicine lacks effective fluid-accumulation to drain away through
treatments for many causes of dementia, the tube and into another body-space
it's also true that still others can be where it causes no harm. Normal pressure
cured or favorably modified. It would be hydrocephalus can be identified not only
a shame to assume that a case was by its dementia and enlarged ventricles,
untreatable and thereby miss something but by the concurrent presence of a
that could have been cured or better prominent walking impairment as well as
managed.So how do dementia specialists or urinary incontinence.Non-surgical
other doctors investigate cases of treatments can be helpful for other
dementia? The medical detective-work causes of dementia. Two conditions
begins with a thorough history and involving a deficiency or shortage of a
physical examination.Clues might come biochemical are hypothyroidism and
from the history of the patient's other vitamin B12 deficiency. Finding one of
medical problems, the medication list, these is a blessing in disguise because
use of alcohol or other drugs, or from they are easily fixed. In hypothyroidism,
other physical problems that developed the thyroid gland in the neck secretes
concurrently with the dementia. Apart too little thyroid hormone. This is
from the general physical exam, the managed by making up for the shortfall in
doctor also explores the patient's pill form. In vitamin B12 deficiency, the
ability to pay attention, remember, problem is that this essential vitamin is
calculate, draw pictures, reason, not properly absorbed into the
comprehend words and express himself or bloodstream via the gastrointestinal
herself. Further neurological examination tract, so the deficiency is treated by
assesses other aspects of brain function periodic injections of vitamin B12.As
like vision, hearing, strength, people get older and acquire more medical
coordination, sensation, walking and problems, their list of medications often
reflexes.After compiling the results of grows longer. One or more of the
the history and examination, the medications they take might interfere
physician can usually judge the relative with mental functioning. Common offenders
likelihoods of different underlying are medications for urinary incontinence,
causes for the dementia, but follows up anxiety or insomnia. If a
these clinical judgments with additional problem-medication is eliminated or
medical tests to nail down the most replaced with another drug, the patient's
likely cause. The irreducible minimum of mental prowess can improve.Depression is
additional testing includes a brain a common cause of dementia in which the
scan--either a CT or an MRI--plus a panel mood disorder itself interferes with
of blood tests.The brain scan might concentration, memory and other mental
detect a brain tumor, previously performance. In many cases the mental
unsuspected strokes, clotted blood impairments are more prominent than the
compressing the brain or hydrocephalus mood disturbance, causing it to be
(water on the brain) all of which can overlooked. Depression is treated with
cause dementia and which can also be medication, psychotherapy, or
treated. The blood tests look for both.Chronic infections with the Lyme and
salt-and-water imbalances, abnormal syphilis bacteria can be resolved with
blood-sugar levels, kidney impairment, appropriate antibiotics. Occasionally a
liver impairment, excessive calcium fungal infection is to blame, and can
levels, thyroid disease, and deficiencies also be treated with specific medication.
of vitamin B12 and folic acid. Each of Treatments for HIV are less good, but
these problems, if found, would warrant this disease still needs to be identified
specific treatment.Other tests can be in order to obtain the best possible
applied depending on the physician's outcome.Chronic alcohol abuse can damage
judgment of their usefulness in the brain and cause dementia. In most
individual cases. These might include an cases the previously caused damage cannot
electroencephalogram (brain-wave test), be undone, but further damage can be
lumbar puncture (spinal tap) or a PET prevented through treatment of the
(positron emission tomographic) scan, alcoholism. Wernicke's encephalopathy is
which is a newer technique that shows the an alcohol-associated cause of confusion
relative activity of brain cells in for which injections of thiamine (vitamin
different parts of the brain. Additional B1) are urgently needed.Strokes can also
blood-tests can screen for infections produce dementia. Strokes are caused by
with human immunodeficiency virus (HIV) disrupted circulation which damages parts
or the bacteria associated with Lyme of the brain. In most cases, the patient
disease or syphilis.After all is said and and family were aware of strokes when
done, what turns up? Unfortunately, about they occurred, but in other cases one or
half the dementia cases evaluated in this more strokes might have gone undetected
way lead to a diagnosis of Alzheimer's at the time they occurred. Prior strokes
disease or similar degenerative brain cannot be undone, but recognition of the
disease for which there is no cure. presence of strokes can lead to
Although treatments exist for these preventive measures to decrease the
degenerative dementias, their benefits likelihood of future strokes.Apart from
are modest.It's the other half of the the conditions and diseases already
cases which reveal an interesting mentioned, the list of potential causes
grab-bag of different underlying causes of dementia is longer still. In brief,
and, for that matter, not every cause of dementia can be cured
treatments.Neurosurgery can be indicated or significantly improved, but without a
for dementias caused by brain tumors, thoughtful, thorough, medical evaluation
especially meningiomas which are the ones that can be treated could easily
slow-growing tumors that respond poorly go undetected.(C) 2005 by Gary
to chemotherapy or radiation therapy, but CordingleyGary Cordingley, MD, PhD, is a
can be totally removed in surgical clinical neurologist, teacher and
operations. Meningiomas are not researcher who works in Athens, Ohio.
cancerous, but because space inside the




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